The first clash between last season's top two, Liverpool and Manchester City, does not take place until November.
Manchester City will not take on Liverpool in the Premier League until November, while the first Manchester derby of the 2019-20 season is set for December.
Pep Guardiola's side, title winners in each of the past two seasons, face Champions League runners-up Tottenham in their first home game of the new campaign on August 17.
City are set to take on Manchester United at home on December 7 before heading to Old Trafford for the return fixture in March. They go to Anfield on November 9 and welcome Liverpool to the Etihad Stadium on April 4.
The first north London derby is scheduled for August 31 at Emirates Stadium, although fixtures are subject to changes for live broadcast, with the return at Tottenham Hotspur Stadium at a crunch time of the season in late April.
A goalless draw at Goodison Park was one of the results that cost Liverpool the chance to usurp City last term and Jurgen Klopp's European champions go to Everton during the run-in again.
Liverpool are away to Everton on March 14 with the Toffees visiting Anfield in early December, while Klopp's men play Arsenal away and Chelsea at home in two of their last three Premier League fixtures.
City's run-in looks more straightforward on paper, but in a testing spell spanning late February to early April that also clashes with the Champions League knockout rounds they are set to play Arsenal, United, Chelsea and Liverpool within five league games.
There will be a mid-season break in 2019-20 with one round of matches in February to be split over two weekends. Which games are moved from February 8 to the following weekend will be decided in December when live broadcast schedules are finalised.
Premier League 2019-20 key fixtures:
August 11, Manchester United v ChelseaAugust 17, Manchester City v TottenhamAugust 24, Liverpool v ArsenalAugust 31, Arsenal v TottenhamSeptember 21, Chelsea v LiverpoolSeptember 28, Manchester United v ArsenalOctober 19, Manchester United v LiverpoolOctober 26, Liverpool v TottenhamNovember 9, Liverpool v Manchester CityNovember 23, Manchester City v ChelseaDecember 3, Manchester United v TottenhamDecember 4, Liverpool v EvertonDecember 7, Manchester City v Manchester UnitedDecember 14, Arsenal v Manchester CityDecember 21, Tottenham v ChelseaDecember 28, Arsenal v Chelsea
January 1, Arsenal v Manchester UnitedJanuary 11, Tottenham v LiverpoolJanuary 18, Liverpool v Manchester UnitedJanuary 22, Chelsea v ArsenalFebruary 1, Tottenham v Manchester CityFebruary 8, Chelsea v Manchester UnitedFebruary 22, Chelsea v TottenhamFebruary 29, Manchester City v ArsenalMarch 7, Manchester United v Manchester CityMarch 14, Everton v LiverpoolMarch 14, Tottenham v Manchester UnitedMarch 21, Chelsea v Manchester CityApril 4, Manchester City v LiverpoolApril 25, Tottenham v ArsenalMay 2, Arsenal v LiverpoolMay 9, Liverpool v Chelsea